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Articles by Carma Spence

Supportive Programs and Services — Going Beyond Treatment

Part of a series of brochures about the various programs offered at City of Hope. City of Hope believes that when a person has cancer, it affects not only the patient, but his or her family and loved ones, as well. Therefore, since its founding in 1913, City of Hope has maintained a commitment to treating the whole person, not just the disease, by offering programs and services that go beyond what has traditionally been associated with hospital care. These efforts reflect the institution’s credo, There is no profit in curing the body, if the in the process you destroy the soul. These services also stand as testimony to City of Hope’s ongoing commitment to its “Thirteen Articles of Faith” formalize the ideology that is City of Hope’s foundation, an ideology that recognizes that illness not only affects a person’s physical well-being, but also his or her mental spiritual and

City of Hope – A Brief History

Created for City of Hope’s press kit, I researched and wrote the content, as well as managed the project. Mission Statement City of Hope, inspired and supported by a philanthropic volunteer movement, is dedicated to the prevention, treatment and cure of cancer and other life-threatening diseases through innovative research and patient care. A Brief History City of Hope was founded in 1913 in Duarte, California, by a small group of working class men and women who believed in helping those less fortunate than themselves. From humble beginnings–two tents erected on 10 acres of desert 25 miles northeast of Los Angeles–City of Hope has expanded to encompass more than 100 peaceful, beautifully gardened acres. In this healing setting, approximately 250 physicians and scientists collaborate to discover, develop and implement innovative strategies for the prevention and treatment of cancer and other catastrophic diseases. City of Hope has historically combined significant philanthropy with

City of Hope Research Landmarks

Created for City of Hope’s press kit, I researched and wrote the content, as well as managed the project. Discovered First Molecular Evidence Linking Cigarette Smoke to Lunch Cancer Researchers at City of Hope’s Beckman Research Institute, in conjunction with researchers at M.D. Anderson Cancer Center, University of Texas, found the first molecular evidence linking benzo(a)pyrene, a specific compound in cigarette smoke, to lung cancer. This evidence directly links a defined cigarette-smoke carcinogen and human cancer. Began First FDA-Approved Human Trials of Gene Therapy for HIV/AIDS A team headed by City of Hope researchers, in collaboration with Childrens Hospital Los Angeles, Ribozyme Pharmaceuticals, Inc. and Chiron Corporation, gained approval from the Food and Drug Administration for human trials of a gene therapy treatment for HIV, the virus that causes AIDS. The therapy uses bone marrow transplantation and ribozymes, “molecular scissors,” specially engineered to recognize and sever the molecular materials necessary

City of Hope Historical Highlights

Created for City of Hope’s press kit, I researched and wrote the content, as well as managed the project. 1913 – The Jewish Consumptive Relief Association (JCRA)–the precursor to City of Hope–buys 10 acres in Duarte, California, to establish a nonsectarian, free-care tuberculosis sanatorium. 1914 – Cornerstone for “City of Hope” laid. 1915 – First cottage erected to accommodate three patients. 1921 – First stucco structure built, named the “San Francisco building,” in honor of the distant friends who had paid for it. 1926 – Samual H. Golter named executive director of City of Hope. Grace Medical Library is built. The building now houses City of Hope’s Graphic Services Department. For the complete document, download full PDF.

Arthur D. Riggs, PhD, Coedits Monograph on Epigenetics

This article was published in the Monday, May 5, 1997 issue of F.Y.I., City of Hope’s weekly employee newsletter. Epigenetics, the study of heritable processes not directly dependent on DNA base sequences, is an emerging discipline of Biology. Arther D. Riggs, PhD, director, Department of Biology, has coedited a recently published monograph on this topic, titled Epigenetic Mechanisms of Gene Regulation (1997, Cold Spring Harbor Laboratory Press, $125). “Many heritable changes in gene function are not explained by changes in the DNA sequence,” say the publishers of the monograph… Download the full article here.

What’s in a Name?

This article was a special attachment to the the weekly employee newsletter, F.Y.I., at City of Hope National Medical Center. What’s in a Name? CRIIS Promotes Information Sharing City of Hope holds the distinction of being the first free-standing Cancer Center to be awarded an Integrated Advanced Information Management Systems (IAIMS) Planning Grant. “CRIIS”, which stands for Clinical and Research Integrated Information Systems, is the unique name chosen by City of Hope for its IAIMS program. IAIMS is a program sponsored by the National Library of Medicine (NLM) to fund and promote the development of fully integrated computer systems in academic settings. CRIIS’S primary purpose will be to support the global vision of City of Hope as being patient-centered, research-driven, and business-oriented. Because the CRIIS program will continue to grow beyond IAIMS grant funding, it’s important for us to build the CRIIS name recognition. So, spread the word! Continue reading

Pioneering Researcher Reflects on the Past and Looks to the Future

An article published in Cancer Center Research Report, Spring/Summer 1996, pp 13-15, by City of Hope Clinical Cancer Research Center and the Beckman Research Institute. Download the formatted version here. Pioneering Researcher Reflects on the Past and Looks to the Future –Susumu Ohno, DVM, PhD, DSc, Distinguished Scientist, Retires from City of Hope There are leaders as well as followers; then there are pioneers. One such pioneer is Susumu Ohno, DVM, PhD, DSc, distinguished scientist in the Division of Biology at City of Hope’s Beckman Research Institute. In March, Dr. Ohno announced his retirement from City of Hope, bringing to a close an association that has lasted more than 40 years. While at City of Hope, Dr. Ohno made seminal contributions to the field of modern biology-contributions that have garnered him international recognition and distinction. A scientist to the core, he emphasizes that although he is retiring from City of

Projects Managed: A Celebration of Life 1996

City of Hope’s first bone marrow transplant took place on May 18, 1976. In 1996, the Cancer Center celebrated the 20-year anniversary of the transplant program, including an appearance of the first transplant patient. To commemorate this special Celebration of Life, which had become an annual event, this special book was created. I managed its production, coordinating content, design and production, as well as editing the program. Table of Contents Preface A Brief History of Bone Marrow Transplantation, Worldwide and at City of Hope Twenty Years in Review: Landmarks for City of Hope’s Bone Marrow Transplantation Program The Origins of City of Hope’s Bone Marry Transplantation Program Ernest Beutler, MD Karl G. Blume, MD Our Patients and Their Stories Memories and Inspirations A Memorial Tribute to Gerhard M. Schmidt, MD Placed in the Hands of Many Yesterday’s Patients Look to the Future Specs 8-1/2″ x 11 Perfect bound 86 pages

Diabetes Dialogue

Diabetes Dialogue was a quarterly patient newsletter for the Department of Diabetes, Endocrinology & Metabolism. My responsibilities were to copy edit, work with the designer to produce, and manage the process from raw copy to produced piece. Generally, this newsletter was four pages, including the cover and back. Occasionally, it grew to six pages and was folded brochure style. Download sample issues: Spring 1996 Winter 1996 Spring 1998