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City of Hope Research Landmarks

research-landmarksCreated for City of Hope’s press kit, I researched and wrote the content, as well as managed the project.

Discovered First Molecular Evidence Linking Cigarette Smoke to Lunch Cancer
Researchers at City of Hope’s Beckman Research Institute, in conjunction with researchers at M.D. Anderson Cancer Center, University of Texas, found the first molecular evidence linking benzo(a)pyrene, a specific compound in cigarette smoke, to lung cancer. This evidence directly links a defined cigarette-smoke carcinogen and human cancer.

Began First FDA-Approved Human Trials of Gene Therapy for HIV/AIDS
A team headed by City of Hope researchers, in collaboration with Childrens Hospital Los Angeles, Ribozyme Pharmaceuticals, Inc. and Chiron Corporation, gained approval from the Food and Drug Administration for human trials of a gene therapy treatment for HIV, the virus that causes AIDS. The therapy uses bone marrow transplantation and ribozymes, “molecular scissors,” specially engineered to recognize and sever the molecular materials necessary for HIV to replicate, in an attempt to confer long-lasting, or even permanent, control of HIV for those infected.

Developed the Theory of Evolution by Gene Duplication
Evolution is dependent on the development of new genes. A City of Hope researcher developed a theory, published in the 1970 book Evolution by Gene Duplication, which explained how new genes develop. This theory, which is the basis of much biological research, is now widely accepted in the scientific community.

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