Article from CityLink, February 1998, back page. Published by City of Hope National Medical Center, Office of Public and Government Affairs, 1500 East Duarte Road, Duarte, CA 91010
Maneuvering Around the Hairpins and Loops of DNA
Scientists Reveal New Insight into Cancer Development
An enzyme makes its way down a molecule of DNA (the master molecule that contains the genetic code and controls a cell’s activity), moving along the spiral staircase with ease. Then suddenly, it stops. There is a bulge in the DNA — the enzyme has encountered an abnormal structure called a “hairpin” or “loop.” How the enzyme maneuvers around this hairpin could have far-reaching implications for the cell, and ultimately for the person in which the cell resides.